To a small saucepan, add Guinness, ketchup, vegan Worcestershire, orange juice, brown sugar, dijon, salt, pepper, onion powder, garlic powder, chili powder, and paprika.
Bring everything to a boil, and then reduce heat to a rolling simmer. Allow it to simmer for about 10 mins, stirring occasionally.
Remove from the heat, add orange zest, and allow the sauce to cool.